Biogen and TheraPanacea Announce New Collaboration

Read the press release here.

 

Biogen and TheraPanacea Announce New Collaboration with the Potential to Advance Digital Health for Personalized Medicine in Neuroscience

 

  • Collaboration aims to develop innovative machine learning and artificial intelligence solutions for personalized and earlier treatment in neurology
  • Biogen to gain exclusive rights to TheraPanacea technology in neuroscience

 

CAMBRIDGE, Mass. and PARIS, Dec. 14, 2021 (GLOBE NEWSWIRE) — Biogen Inc. (Nasdaq: BIIB) and TheraPanacea today announced that they have entered into a collaboration focused on multiple therapeutic areas in neuroscience, to further build on the companies’ existing relationship. The aim is to leverage machine learning (ML) and artificial intelligence (AI) analysis to develop digital health solutions that may improve patient care, accelerate drug development, and further the understanding of the underlying pathologies of neurological diseases.

 

“We believe that neuroscience is at an inflection point for innovation and breakthrough. Advancements in technology may increase our ability to understand disease, target treatments, and manage risk,” said Martin Dubuc, Head of Biogen Digital Health. “Based on the outcome of our prior work with TheraPanacea and their success with AI in oncology, we are excited to further this collaboration. We believe digital health solutions will enable us to pioneer a new era of personalized medicine built upon a foundation of accessibility and precision.”

 

By harnessing ML and AI to draw meaning from medical imaging and other clinically relevant data sources, there is potential to improve disease understanding and enable more personalized clinical trial design. This could result in shortening drug development cycles, lowering associated costs, and increasing probability of success. At the same time, these digital health solutions have the potential to support more informed clinical decisions and could lead to improved health outcomes for patients.

 

“We are excited to collaborate with Biogen and combine our ML and AI solutions with their world-class clinical expertise and unique datasets in neuroscience,” said Professor Nikos Paragios, Chief Executive Officer of TheraPanacea and distinguished professor of mathematics at CentraleSupélec, University of Paris-Saclay. “Through this collaboration, we aim to scale our artificial intelligence multi-omics biomarker discovery platform and deploy clinical solutions that have the potential to deliver better treatment decisions for patients living with neurological diseases.”

 

Under the terms of the agreement, Biogen will invest up to $15 million in exchange for TheraPanacea convertible debt. The agreement also provides for up to approximately $41 million (based on current exchange rates) in milestone payments contingent upon the achievement of certain research and development milestones. In addition, Biogen gains exclusive rights to TheraPanacea’s technology in neuroscience. To meet the goals of this collaboration, TheraPanacea will invest in expanding its existing operations and workforce in Europe.

 

About Biogen

 

As pioneers in neuroscience, Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological diseases as well as related therapeutic adjacencies. One of the world’s first global biotechnology companies, Biogen was founded in 1978 by Charles Weissmann, Heinz Schaller, Sir Kenneth Murray, and Nobel Prize winners Walter Gilbert and Phillip Sharp. Today, Biogen has the leading portfolio of medicines to treat multiple sclerosis, has introduced the first approved treatment for spinal muscular atrophy, and is providing the first and only approved treatment to address a defining pathology of Alzheimer’s disease. Biogen is also commercializing biosimilars and focusing on advancing the industry’s most diversified pipeline in neuroscience that will transform the standard of care for patients in several areas of high unmet need.

 

In 2020, Biogen launched a bold 20-year, $250 million initiative to address the deeply interrelated issues of climate, health, and equity. Healthy Climate, Healthy Lives™ aims to eliminate fossil fuels across the company’s operations, build collaborations with renowned institutions to advance the science to improve human health outcomes, and support underserved communities.

 

We routinely post information that may be important to investors on our website at www.biogen.com. Follow us on social media – TwitterLinkedInFacebookYouTube.

 

Biogen Safe Harbor

 

This news release contains forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about the potential impact of machine learning/artificial intelligence with respect to clinical and health outcomes; the potential benefits from early identification of disease; the potential benefits and results that may be achieved through our collaboration with TheraPanacea; the potential of our commercial business and pipeline programs; and our strategy and plans. These statements may be identified by words such as “aim,” “anticipate,” “believe,” “could,” “estimate,” “expect,” “forecast,” “goal,” “intend,” “may,” “plan,” “possible,” “potential,” “will,” “would” and other words and terms of similar meaning. You should not place undue reliance on these statements, or the scientific data presented.

 

These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements, including without limitation, the risks of unexpected costs or delays; the risk of other unexpected hurdles; failure to protect and enforce our data, intellectual property and other proprietary rights and uncertainties relating to intellectual property claims and challenges; regulatory authorities may require additional information or further studies; third party collaboration risks; and the direct and indirect impacts of the ongoing COVID-19 pandemic on our business, results of operations and financial condition. The foregoing sets forth many, but not all, of the factors that could cause actual results to differ from our expectations in any forward-looking statement. Investors should consider this cautionary statement as well as the risk factors identified in our most recent annual or quarterly report and in other reports we have filed with the U.S. Securities and Exchange Commission. These statements are based on our current beliefs and expectations and speak only as of the date of this news release. We do not undertake any obligation to publicly update any forward-looking statements, whether as a result of new information, future developments or otherwise.

 

 

About TheraPanacea

 

TheraPanacea is a highly innovative information technology company devoted to unlocking the unlimited power of AI-based solutions to drive innovation in healthcare.

 

Spinoff of University of Paris-Saclay, TheraPanacea works in close cooperation with the most prominent healthcare facilities to combine the power of its proprietary platforms with clinical domain-knowledge. Our technology is a unique combination of decisional, domain-constrained, and data-driven artificial intelligence software equipping clinicians and healthcare professionals with the most innovative tools to improve treatment selection, planning, delivery, and outcomes, including biomarker discovery and patient stratification.

 

Using TheraPanacea’s AI-powered clinical solutions (ART-Plan™), healthcare providers experience significant gain in productivity, higher standardization of care, improvement of clinical workflow and better treatment outcomes for cancer patients. TheraPanacea’s AI-powered biomarker discovery platform (ART-Omics™) offers upstream/downstream innovation to pharmaceutical companies through shorter development cycles, decreased costs and higher efficacy.

 

TheraPanacea’s development benefited from the ecosystems of University of Paris Saclay and Paris Biotech Santé while being backed by Therinvest, (Innothera’s independent growth digital health fund) and competitive fundings from the SATT Paris-Saclay, the French Ministry of Higher Education and Research, French Public investment Banque (BPI), the European Research Council (ERC) and the EIC Accelerator from the European Innovation Council.

Philips to expand its cardiac diagnostics and monitoring portfolio with the acquisition of Cardiologs

Read the Article on Philips’ website 

 

Amsterdam, the Netherlands – Cardiologs will further strengthen Philips’ cardiac monitoring and diagnostics offering with innovative software technology, electrocardiogram (ECG) analysis and reporting services. The transaction, which is subject to customary closing conditions, is expected to be completed in the coming months. Financial details of the transaction were not disclosed.

 

The acquisition of Cardiologs is a strong fit with Philips’ existing portfolio of cardiac care solutions. This includes real-time patient monitoring, therapeutic devices, telehealth and informatics for the hospital, as well as ambulatory cardiac diagnostics and monitoring solutions, that were added through the recent acquisition of BioTelemetry, Inc.

 

Cardiologs will complement this offering with a vendor-neutral heart disorder screener and ECG analysis applications, based on machine learning algorithms. Developed in partnership with leading physicians, Cardiologs’ technology accelerates diagnostic reporting, decreases the occurrence of reporting errors and streamlines clinician workflow and patient care, empowering clinicians to deliver expert cardiac care faster and more efficiently. CE-marked and FDA cleared for detection of cardiac arrhythmias, Cardiologs’ technology is built on a growing database of more than 20 million ECG recordings and supported by a number of clinical publications.

Offering superb clinical insights, as well as automated clinical reporting, Cardiologs’ medical-grade AI technology and data scientists will be a strong addition to our growing portfolio of cardiac solutions for hospital and ambulatory settings.
Roy Jakobs

 

“Offering superb clinical insights, as well as automated clinical reporting, Cardiologs’ medical-grade AI technology and data scientists will be a strong addition to our growing portfolio of cardiac solutions for hospital and ambulatory settings,” said Roy Jakobs, Chief Business Leader Connected Care at Royal Philips.

 

Philips’ global footprint can accelerate the availability of Cardiologs’ technology to patients all over the world and further deliver on the quadruple aim of an improved patient care experience, better health outcomes, improved staff experience, and lower cost of care.”

 

“We are delighted to become part of Philips and continue innovating together to provide solutions that empower clinicians all around the world,” said Yann Fleureau, Co-Founder and CEO of Cardiologs. “We look forward to the opportunity to expand the business as part of Philips, maintaining vendor neutrality and continuing to work with third party vendors to drive further adoption of digital health solutions globally.”

 

Cardiologs was founded in 2014 and is headquartered in Paris, France. Its approximately 70 employees, largely comprising software engineers and data scientists with expertise in AI and deep learning algorithms, will join Philips and will expand the company’s continued AI-focused innovation activities together with the company’s R&D lab in Paris. Philips has a strong presence in France, consisting of research and development activities, as well as sales, marketing and distribution at multiple sites.

Joffe & Associés distingué dans le classement Décideurs

Le magazine Décideurs, paru en juillet 2021, classe le cabinet Joffe & Associés :

  • Incontournable en Capital-Innovation (équipe animée par Aymeric DEGREMONT, Virginie BELLE, Thomas SALTIEL et Christophe JOFFE)
  • Excellent en LBO – Small-Cap (équipe animée par Aymeric DEGREMONT, Virginie BELLE, Thomas SALTIEL et Christophe JOFFE)
  • Excellent en Structuration et Création de Fonds (équipe animée par Olivier DUMAS)
  • Forte notoriété en Fiscalité des LBO (équipe animée par Virginie DAVION)

Félicitations à nos équipes pour cette belle performance !

J&A classé dans l’édition 2021 du Legal 500

Voir le classement sur le site du Legal 500

INDUSTRY FOCUS: LUXURY GOODS TIER 1

Full-service corporate firm Joffe & Associés‘ luxury goods practice represents a diverse client base featuring French and European flagship brands in cosmetics, jewellery and perfume. Thomas Lepeytre, who is a recognised specialist in commercial and distribution law, leads the department. Complementary expertise at the firm spans employment, tax, IP and IT law, making it a one stop-shop for many of the practice’s longstanding clients.

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MEDIA AND ENTERTAINMENT: SPORTS TIER 1

Recognised for its proficiency in advising on media rights and sports events organisation, Joffe & Associés acts as strategic adviser to some of France’s highest profile leagues and federations including the French Handball League, the French Professional Football League and the French Athletics Federation. The full-service offering at the firm means the team is able to advise on a wide variety of matters ranging from assisting investors with the acquisition of French football clubs, to representing the FFF in litigation brought against third-part ticket resellers. Romain Soiron is the key name, working exclusively on sports matters, with good experience negotiating sponsorships and broadcasting rights.

Practice head(s):

Romain Soiron

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INTELLECTUAL PROPERTY: COPYRIGHT

Rising stars

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ADMINISTRATIVE AND PUBLIC LAW TIER 3

Joffe & Associés assists major public sector operators as well as local entities and major private companies. Headed by Mathieu Gaudemet, the practice has solid expertise in public contracts, urban planning, state aid and regulatory matters. The team is handling highly strategic work in the transport sector, notably in the rail sector, and shoulders a busy litigation caseload.

Practice head(s):

Mathieu Gaudemet

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PRIVATE EQUITY: FUND FORMATION TIER 3

Practice head(s):

Olivier Dumas

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PRIVATE EQUITY: VENTURE/GROWTH CAPITAL TIER 3

MERGERS AND ACQUISITIONS TIER 5

Practice head(s):

Virginie Belle, Aymeric Dégremont, Christophe Joffe et Thomas Saltiel

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DISPUTE RESOLUTION: COMMERCIAL LITIGATION TIER 4

Joffe & Associés

Practice head(s):

Fabrice Hercot; Tehani Goy

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EMPLOYMENT TIER 4

Joffe & Associés

Practice head(s):

Géraldine Lepeytre; Blaise Deltombe

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EU, COMPETITION AND DISTRIBUTION TIER 4

Joffe & Associés is a strong merger control practice, able to advise on cross-border matters, particularly for private equity firms. The team has handled abuse of dominance and cartel investigations and related litigation, as well as distribution matters. In recent years it has been increasingly involved in follow-on damages claims. Practice head Olivier Cavézian is experienced in acting for major domestic and international clients.

Practice head(s):

Olivier Cavézian

J&A classé dans le Palmarès du Point

Joffe & Associés est, cette année encore, classé parmi les meilleurs cabinets de la place en :

– Private equity et venture capital

– Droit des sociétés

– Droit commercial, des affaires et de la concurrence

Merci à nos clients et confrères d’avoir voté pour nous et bravo à nos équipes !

 

Olivier Dumas quitte Dechert pour intégrer Joffe & Associés

Son expertise se concentre notamment sur les dossiers liés à la structuration de fonds d’investissement, d’opérations liées à la vie des fonds et leurs gestionnaires, aux opérations d’investissement qu’ils réalisent, ainsi qu’aux problématiques réglementaires qui encadrent leurs activités. Ses clients sont des gestionnaires d’actifs, des prestataires du secteur financier, ainsi que des investisseurs français et étrangers.

Olivier Dumas devient ainsi le quatorzième associé du cabinet : « Je suis ravi de rejoindre une structure dont je partage les valeurs, notamment dans le travail collectif, l’intérêt pour les dossiers et les rapports noués avec les clients. Je connais ce cabinet ainsi que certain de ses associés depuis longtemps. Christophe Joffe, son fondateur, et moi nous avions des clients en commun de longue date ».

Il vient ainsi compléter l’expertise de ce dernier, plutôt axé sur le capital-développement, ainsi que celle de Virginie Belle et Thomas Saltiel, positionnés sur le capital-risque, et d’Aymeric Dégremont, actif à la fois en capital-risque et LBO. Associé chez SGDM pendant six ans, Olivier Dumas rejoint ensuite Proskauer Rose en 2007, puis Dechert deux ans plus tard (2009-2017). Il est titulaire d’un DEA de droit économique (université Paris Dauphine, 1991) et d’un Master de droit des affaires (université Paris I, 1990).